mitobronitol

Mitobronitol (1,6-dibromo-1,6-dideoxy-D-mannitol) is a brominated analog of mannitol. It is an anticancer drug that is also classified as an alkylating agent.

Research

59 papers

Mitobronitol: an alkylating agent that does not induce extra leukemia cases if applied as pulse therapy for polycythemia vera.Annals of the New York Academy of Sciences · 1985
Non-supralethal mitobronitol/cytarabine/cyclophosphamide conditioning without irradiation before bone marrow transplantation for accelerated chronic granulocytic leukemia: apparent absence of acute graft-versus-host disease.Leukemia · 1993
Multiple granulocytic sarcomas in essential thrombocythemia.International journal of hematology · 2006
Comparison of the lymphoid toxicities of mitobronitol and busulphan in mice: reduced B cell toxicity and improved thymic recovery as possible contributors to the reduced risk for complications following BMT with mitobronitol preconditioning.Leukemia · 1997
Anticancer chemotherapy.British medical journal (Clinical research ed.) · 1983

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Wikidata facts

Mass: 305.910233064

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chemical formula: C₆H₁₂Br₂O₄
canonical SMILES: C(C(C(C(C(CBr)O)O)O)O)Br
isomeric SMILES: O[C@@H]([C@H](O)[C@H](O)CBr)[C@H](O)CBr

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References

Mitobronitol (1,6-dibromo-1,6-dideoxy-D-mannitol) is a brominated analog of mannitol. It is an anticancer drug that is also classified as an alkylating agent.

==References==