mitochondrial DNA
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AI overview
Mitochondria are tiny structures inside our cells that contain their own DNA, separate from the DNA in the cell nucleus. This mitochondrial DNA is important because mitochondria generate the energy our cells need to function, making it essential for life.
AI-generated from the Wikipedia summary — may contain errors.
Research
114,149 papers- Mitochondrial DNA Integrity: Role in Health and Disease.Cells · 2019
- Structure, mechanism, and regulation of mitochondrial DNA transcription initiation.The Journal of biological chemistry · 2020
- Mitochondrial DNA Analysis.Methods in molecular biology (Clifton, N.J.) · 2023
- Mitochondrial DNA damage, repair, and replacement in cancer.Trends in cancer · 2025
- Mitochondrial DNA Instability in Mammalian Cells.Antioxidants & redox signaling · 2022
via PubMed
Article
Mitochondrial DNA is the small circular chromosome found inside mitochondria. These organelles, found in most eukaryotic cells, are the powerhouse of the cell. The mitochondria, and thus mitochondrial DNA, are passed exclusively from mother to offspring through the egg cell.
Illustration of the location of mitochondrial DNA in human cells Electron microscopy reveals mitochondrial DNA in discrete foci. Bars: 200 nm. (A) Cytoplasmic section after immunogold labelling with anti-DNA; gold particles marking mtDNA are found near the mitochondrial membrane (black dots in the upper right). (B) Whole mount view of cytoplasm after extraction with CSK buffer and immunogold labelling with anti-DNA; mtDNA (marked by gold particles) resists extraction. From Iborra et al., 2004.