File:Modafinil_structure.svg · Wikimedia Commons · See Wikimedia Commons
مدافینیل
Sign in to saveAlso known as Provigil®, 2-((diphenylmethyl)sulfinyl)acetamide, Modafinilum, Modafinilo, Modafinil, Moderateafinil, Alertec
یک داروی محرک سیستم اعصاب مرکزی
OverviewAI-generated
Modafinil is a chemical compound with the formula C₁₅H₁₅NO₂S. Its IUPAC name is 2-benzhydrylsulfinylacetamide. The substance has a mass of 273.08235 and a weight of 273.4. It possesses a defined daily dose of 0.3.
Chemical properties include an xlogp value of 1.7 and a topological polar surface area of 79.4. The molecule contains one hydrogen bond donor and three hydrogen bond acceptors, with a charge of 0. The canonical SMILES representation is C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N.
Modafinil is referenced by 1,549 other encyclopedia articles. It has 40,956 social media followers. A search query for modafinil yields 2,378 results.
Synthesized by Vinony from 19 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.image
- Modafinil structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 215px
- Drug.caption
- Modafinil skeletal formula
- Drug.image2
- (S)-Modafinil molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 225px
- Drug.caption2
- Esmodafinil ball-and-stick model
- Drug.tradename
- Provigil, others
- Drug.MedlinePlus
- a602016
- Drug.DailyMedID
- Modafinil
- Drug.pregnancy_AU
- D
- Drug.dependency_liability
- Relatively low
- Drug.addiction_liability
- Low
- Drug.routes_of_administration
- Oral (tablets)
- Drug.ATC_prefix
- N06
- Drug.ATC_suffix
- BA07
- Drug.legal_AU
- S4
via Wikipedia infobox
Chemical data
- Formula
- C15H15NO2S
- Molecular weight
- 273.4 g/mol
- IUPAC name
- 2-benzhydrylsulfinylacetamide
- SMILES
- C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N
- InChIKey
- YFGHCGITMMYXAQ-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 79.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1998
- Admin. routes
- oral
- Indications
- attention deficit hyperactivity disorder, cocaine dependence, methamphetamine dependence, brain neoplasm
via ChEMBL · EBI
Research
2,378 papers- Modafinil for poststroke patients: A systematic review.International journal of clinical practice · 2019
- Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine.Psychopharmacology · 2021
- Modafinil and orexin system: interactions and medico-legal considerations.Frontiers in bioscience (Landmark edition) · 2019
- Modafinil Versus Amphetamine-Dextroamphetamine For Idiopathic Hypersomnia and Narcolepsy Type 2: A Randomized, Blinded, Non-inferiority Trial.CNS drugs · 2024
- Repurposing of modafinil as an anti-inflammatory drug: a systematic review of experimental studies.Naunyn-Schmiedeberg's archives of pharmacology · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 273.08235
Show 9 more facts
- chemical formula
- C₁₅H₁₅NO₂S
- medical condition treated
- narcolepsy
- Commons category
- Modafinil
- canonical SMILES
- C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N
- defined daily dose
- 0.3
- subject has role
- nootropic
- social media followers
- 40956
- legal status (medicine)
- boxed warning
- used by
- United States Air Force
Sources (9)
via Wikidata · CC0