MTNR1A

Name

melatonin receptor 1A

Type

protein-coding

Position

186,526,792–186,555,567 (−)

Aliases

MEL-1A-R, MT1

Ensembl

ENSG00000168412

RefSeq RNA

NM_005958.4, XM_011532002.4, XM_054350094.1

RefSeq protein

NP_005949.1, XP_011530304.1, XP_054206069.1

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

melatonin receptor 1A

Symbol

MTNR1A

Biotype

Protein coding

Organism

Homo sapiens

Location

4:186,526,792-186,555,567

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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