EntityQ1215575· pop 50· linked from 688 articles

naproxen

Naproxen, sold under the brand name Aleve among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, and inflammatory diseases such as rheumatoid arthritis, gout and fever. It is taken orally. It is available in immediate and delayed release formulations. Onset of effects is within an hour and lasts for up to twelve hours. Naproxen is also available in salt form, naproxen sodium, which has better solubility when taken orally.

Key facts

Drug.Watchedfields: changed
Drug.verifiedrevid: 464372587
Drug.image: Naproxen2DACS.svg
Drug.image_class: skin-invert-image
Drug.width: 200
Drug.image2: (S)-naproxen-from-xtal-3D-bs-17.png
Drug.image_class2: bg-transparent
Drug.tradename: Aleve, Naprosyn, others
Drug.MedlinePlus: a681029
Drug.DailyMedID: Naproxen
Drug.pregnancy_AU: C
Drug.routes_of_administration: By mouth
Drug.ATC_prefix: G02
Drug.ATC_suffix: CC02
Drug.ATC_supplemental: , , ,
Drug.legal_AU: S2
Drug.legal_AU_comment: when in preparations that contain no more than 15 days' supply. Otherwise it is Schedule 4 (Prescription only).
Drug.legal_CA: OTC / Rx-only

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Article

22 sections

Contents

Medical uses
Available formulations
Pregnancy and lactation
Adverse effects
Gastrointestinal
Cardiovascular
Drug-drug interactions
Pharmacology
Mechanism of action
Pharmacokinetics
Pharmacogenetics
Chemistry
Synthesis
Society and culture
Brand names
Access restrictions
Ecological effects
Research
Veterinary use
Horses
References
External links

Common side effects include dizziness, headache, bruising, allergic reactions, heartburn, and stomach pain. Severe side effects include an increased risk of heart disease, stroke, gastrointestinal bleeding, and stomach ulcers. The heart disease risk may be lower than with other NSAIDs. It is not recommended in people with kidney problems. Use is not recommended in the third trimester of pregnancy.