NEO1
Sign in to saveAlso known as IGDCC2, NGN, NTN1R2, neogenin 1
Neogenin is a protein that in humans is encoded by the NEO1 gene.
Gene data
NEO1- Name
- neogenin 1
- Type
- protein-coding
- Position
- 73,051,645–73,305,205 (+)
- Aliases
- IGDCC2, NGN, NTN1R2
- Ensembl
- ENSG00000067141
- RefSeq RNA
- NM_001172623.2, NM_001172624.2, NM_001419531.1, NM_002499.4, XM_011521628.3
- RefSeq protein
- NP_001166094.1, NP_001166095.1, NP_001406460.1, NP_002490.2, XP_011519930.1
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
neogenin 1
- Symbol
- NEO1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:73,051,645-73,305,205
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein NEO1 PDB 1x5f.png
Show 5 more facts
- HomoloGene ID
- 1870
- exact match
- identifiers.org/ncbigene/4756
- genomic end
- 73305205
- genomic start
- 73344051
- cytogenetic location
- 15q24.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Neogenin is a protein that in humans is encoded by the NEO1 gene.
== Interactions ==