NHP2

Also known as DKCB2, NHP2P, NOLA2, NHP2 ribonucleoprotein

H/ACA ribonucleoprotein complex subunit 2 is a protein that in humans is encoded by the NHP2 gene.

In the Vinony graph

Vinony's link graph records 4 inbound references to NHP2, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 5.

Vinony links it to 6 Wikipedia language editions.

Gene data

NHP2

Name: NHP2 ribonucleoprotein
Type: protein-coding
Position: 178,139,872–178,153,968 (−)
Aliases: DKCB2, NHP2P, NOLA2
Ensembl: ENSG00000145912
RefSeq RNA: NM_001034833.2, NM_001396110.1, NM_017838.4
RefSeq protein: NP_001030005.1, NP_001383039.1, NP_060308.1

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008].

Pathways

Ribosome biogenesis in eukaryotes - Homo sapiens (human)Telomere Maintenance Cell Cycle Telomere Extension By Telomerase Extension of Telomeres rRNA modification in the nucleus and cytosol rRNA processing Chromosome Maintenance rRNA processing in the nucleus and cytosol Metabolism of RNA

via MyGene.info

Gene · Ensembl

NHP2 ribonucleoprotein

Symbol: NHP2
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:178,139,872-178,153,968
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 5524
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/55651
genomic end: 178153894
genomic start: 178149463
chromosome: human chromosome 5
cytogenetic location: 5q35.3

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

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Contents

Identifiers
References
Further reading

H/ACA ribonucleoprotein complex subunit 2 is a protein that in humans is encoded by the NHP2 gene.

== Identifiers == This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA.

Excerpted from Wikipedia’s “NHP2” article, available under the CC BY-SA 4.0 licence.