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GeneQ18049667· pop 5· linked from 26 articles

Also known as CLR19.8, MATER, NALP5, PAN11, PYPAF8, NLR family, pyrin domain containing 5, NLR family pyrin domain containing 5

NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals.

Gene data

NLRP5
Name
NLR family pyrin domain containing 5
Type
protein-coding
Aliases
CLR19.8, MATER, NALP5, OZEMA19, PAN11, PYPAF8

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

NLR family pyrin domain containing 5

Symbol
NLRP5
Biotype
Protein coding
Organism
Homo sapiens
Location
19:55,986,775-56,061,810
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
65105
genomic end
56061810
genomic start
56511092
cytogenetic location
19q13.43
Sources (4)

via Wikidata · CC0

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  • Further reading

NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals.

In humans, the NLRP5 protein is encoded by the NLRP5 gene.

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