NLRP5
Sign in to saveAlso known as CLR19.8, MATER, NALP5, PAN11, PYPAF8, NLR family, pyrin domain containing 5, NLR family pyrin domain containing 5
NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals.
In the Vinony graph
Within Vinony's link graph, NLRP5 is referenced by 26 other articles, and connects out to Q180686, Ensembl genome database project and mammal.
It sits within the topics Genes on human chromosome 19, LRR proteins and NOD-like receptors.
Its subject is documented across 5 Wikipedia language editions.
Gene data
NLRP5- Name
- NLR family pyrin domain containing 5
- Type
- protein-coding
- Position
- 55,986,775–56,061,810 (+)
- Aliases
- CLR19.8, MATER, NALP5, OZEMA19, PAN11, PYPAF8
- Ensembl
- ENSG00000171487
- RefSeq RNA
- NM_001433705.1, NM_153447.4
- RefSeq protein
- NP_001420634.1
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
NLR family pyrin domain containing 5
- Symbol
- NLRP5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:55,986,775-56,061,810
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 65105
- exact match
- identifiers.org/ncbigene/126206
- genomic end
- 56061810
- genomic start
- 56511092
- cytogenetic location
- 19q13.43
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals.
In humans, the NLRP5 protein is encoded by the NLRP5 gene.
Excerpted from Wikipedia’s “NLRP5” article, available under the CC BY-SA 4.0 licence.