NLRC4
Sign in to saveAlso known as CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1
NLR family CARD domain-containing protein 4 is a protein that in humans is encoded by the NLRC4 gene.
Gene data
NLRC4- Name
- NLR family CARD domain containing 4
- Type
- protein-coding
- Aliases
- AIFEC, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, FCAS4
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 10924
- exact match
- identifiers.org/ncbigene/58484
- genomic end
- 32265732
- genomic start
- 32449522
- cytogenetic location
- 2p22.3
Sources (7)
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Structure
- Function
- Interactions
- Clinical significance
- References
- Further reading
NLR family CARD domain-containing protein 4 is a protein that in humans is encoded by the NLRC4 gene.
== Structure ==
Connections
Q180686
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human chromosome 2
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Ensembl genome database project
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protein
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Wikidata
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gene
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chromosome
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digital object identifier
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apoptotic process
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bibcode
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human genome
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Q229883
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base pair
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locus
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gene expression
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Caenorhabditis elegans
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Online Mendelian Inheritance in Man
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Protein Data Bank
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Q22908627
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N-terminus
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