NLRP9
Sign in to saveAlso known as CLR19.1, NALP9, NOD6, PAN12, NLR family, pyrin domain containing 9, NLR family pyrin domain containing 9
NLRP9, short for NOD-like receptor family pyrin domain containing 9, is an intracellular protein that is expressed in the ovaries, testes, oocytes, and preimplantation embryos of mammals that is likely involved in reproductive processes. It is also known as NALP9, NOD6, PAN12, and CLR19.1, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.
Gene data
NLRP9- Name
- NLR family pyrin domain containing 9
- Type
- protein-coding
- Position
- 55,708,438–55,738,402 (−)
- Aliases
- CLR19.1, NALP9, NOD6, PAN12
- Ensembl
- ENSG00000185792
- RefSeq RNA
- NM_176820.4
- RefSeq protein
- NP_789790.2
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
NLR family pyrin domain containing 9
- Symbol
- NLRP9
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:55,708,438-55,738,402
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 18530
- exact match
- identifiers.org/ncbigene/338321
- genomic end
- 56249768
- genomic start
- 55708438
- cytogenetic location
- 19q13.42
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
NLRP9, short for NOD-like receptor family pyrin domain containing 9, is an intracellular protein that is expressed in the ovaries, testes, oocytes, and preimplantation embryos of mammals that is likely involved in reproductive processes. It is also known as NALP9, NOD6, PAN12, and CLR19.1, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.
==References==