Structure via PubChem · Public domain (PubChem)
olutasidenib
Sign in to saveAlso known as Rezlidhia, 5-[[(1S)-1-(6-chloro-2-oxo-1H-quinolin-3-yl)ethyl]amino]-1-methyl-6-oxopyridine-2-carbonitrile
Olutasidenib, sold under the brand name Rezlidhia, is an anticancer medication used to treat relapsed or refractory acute myeloid leukemia with a susceptible IDH1 mutation. Olutasidenib is an isocitrate dehydrogenase-1 (IDH1) inhibitor. It is taken by mouth.
In the Vinony graph
Within Vinony's link graph, olutasidenib is referenced by 271 other articles, and connects out to chemotherapy, tiazofurin and public domain.
It is catalogued under topics including 2-Pyridones, 2-Quinolones and Antineoplastic drugs.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C18H15ClN4O2
- Molecular weight
- 354.8 g/mol
- IUPAC name
- 5-[[(1S)-1-(6-chloro-2-oxo-1H-quinolin-3-yl)ethyl]amino]-1-methyl-6-oxopyridine-2-carbonitrile
- SMILES
- C[C@@H](C1=CC2=C(C=CC(=C2)Cl)NC1=O)NC3=CC=C(N(C3=O)C)C#N
- InChIKey
- NEQYWYXGTJDAKR-JTQLQIEISA-N
- XLogP
- 2.5
- Polar surface area
- 85.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 354.0883534000001
Show 4 more facts
- isomeric SMILES
- C[C@@H](C1=CC2=C(C=CC(=C2)Cl)NC1=O)NC3=CC=C(N(C3=O)C)C#N
- chemical formula
- C₁₈H₁₅ClN₄O₂
- canonical SMILES
- CC(C1=Cc2cc(ccc2NC1=O)Cl)NC3=CC=C(N(C3=O)C)C#N
- legal status (medicine)
- boxed warning
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Medical uses
- Society and culture
- Names
- References
- Further reading
- External links
{{Infobox drug | image = Olutasidenib.svg | image_class = skin-invert-image | width = | alt = | caption =
| pronounce = | tradename = Rezlidhia | Drugs.com = | MedlinePlus = | DailyMedID = Olutasidenib | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATC_prefix = L01 | ATC_suffix = XM03 | ATC_supplemental =
Excerpted from Wikipedia’s “olutasidenib” article, available under the CC BY-SA 4.0 licence.