OSBPL5

Also known as OBPH1, ORP5, oxysterol binding protein like 5

Oxysterol-binding protein-related protein 5 is a protein that in humans is encoded by the OSBPL5 gene.

In the Vinony graph

Within Vinony's link graph, OSBPL5 is referenced by 3 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 11.

Its subject is documented across 6 Wikipedia language editions.

Gene data

OSBPL5

Name: oxysterol binding protein like 5
Type: protein-coding
Position: 3,087,107–3,166,739 (−)
Aliases: OBPH1, ORP5
Ensembl: ENSG00000021762
RefSeq RNA: NM_001144063.2, NM_020896.4, NM_145638.3, XM_011519873.4, XM_017017163.3
RefSeq protein: NP_001137535.1, NP_065947.1, NP_663613.1, XP_011518175.1, XP_016872652.1

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010].

Pathways

Cholesterol metabolism - Homo sapiens (human)Metabolism Acyl chain remodelling of PS Glycerophospholipid biosynthesis Phospholipid metabolism Metabolism of lipids

via MyGene.info

Gene · Ensembl

oxysterol binding protein like 5

Symbol: OSBPL5
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:3,087,107-3,166,739
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 98024
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/114879
genomic end: 3187969
genomic start: 3087107
chromosome: human chromosome 11
cytogenetic location: 11p15.4

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Oxysterol-binding protein-related protein 5 is a protein that in humans is encoded by the OSBPL5 gene.

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified.

Excerpted from Wikipedia’s “OSBPL5” article, available under the CC BY-SA 4.0 licence.