OSBP2
Sign in to saveAlso known as HLM, ORP-4, ORP4, OSBPL1, OSBPL4, oxysterol binding protein 2
Oxysterol-binding protein 2 is a protein that in humans is encoded by the OSBP2 gene.
Gene data
OSBP2- Name
- oxysterol binding protein 2
- Type
- protein-coding
- Aliases
- HLM, ORP-4, ORP2, ORP4, OSBPL1, OSBPL4
The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 75303
- exact match
- identifiers.org/ncbigene/23762
- genomic start
- 31089769
- genomic end
- 31303811
- cytogenetic location
- 22q12.2
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- Further reading
Oxysterol-binding protein 2 is a protein that in humans is encoded by the OSBP2 gene.
Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized.