Also known as MEKA, PHD, PhLOP, PhLP, phosducin
Phosducin, also known as PDC, is a human protein and gene. It belongs to the phosducin family of proteins.
In the Vinony graph
Vinony's link graph records 8 inbound references to PDC, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 9 Wikipedia language editions.
Gene data
PDC- Name
- phosducin
- Type
- protein-coding
- Position
- 186,443,566–186,461,114 (−)
- Aliases
- MEKA, PHD, PhLOP, PhLP
- Ensembl
- ENSG00000116703
- RefSeq RNA
- NM_002597.5, NM_022576.4, NM_022577.1
- RefSeq protein
- NP_002588.3, NP_072098.1
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
phosducin
- Symbol
- PDC
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:186,443,566-186,461,114
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PDC PDB 2trc.png
Show 8 more facts
- HomoloGene ID
- 1950
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5132
- genomic end
- 186461114
- genomic start
- 186412698
- chromosome
- human chromosome 1
- cytogenetic location
- 1q31.1
- expressed in
- striated muscle tissue
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Phosducin, also known as PDC, is a human protein and gene. It belongs to the phosducin family of proteins.
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. By associating with these subunits only, the transducin alpha subunit will remain active for longer. This will increase the amount of time of visual excitation.
Excerpted from Wikipedia’s “PDC” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
via Wikidata sitelinks · CC0