PDGFD
Sign in to saveAlso known as IEGF, SCDGF-B, SCDGFB, MSTP036, platelet derived growth factor D
Platelet-derived growth factor D is a protein that in humans is encoded by the PDGFD gene.
In the Vinony graph
Within Vinony's link graph, PDGFD is referenced by 366 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PDGFD- Name
- platelet derived growth factor D
- Type
- protein-coding
- Position
- 103,865,045–104,164,391 (−)
- Aliases
- IEGF, MSTP036, SCDGF-B, SCDGFB
- Ensembl
- ENSG00000170962
- RefSeq RNA
- NM_025208.5, NM_033135.4
- RefSeq protein
- NP_079484.1, NP_149126.1
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
platelet derived growth factor D
- Symbol
- PDGFD
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:103,865,045-104,164,391
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 11875
- genomic end
- 104035107
- genetic association
- coronary artery disease
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/80310
- genomic start
- 103907189
- chromosome
- human chromosome 11
- cytogenetic location
- 11q22.3
- expressed in
- ascending aorta
via Wikidata · CC0
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Encyclopedic overview
2 sectionsContents
- References
- Further reading
Platelet-derived growth factor D is a protein that in humans is encoded by the PDGFD gene.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.
Excerpted from Wikipedia’s “PDGFD” article, available under the CC BY-SA 4.0 licence.