Structure via PubChem · Public domain (PubChem)
pemafibrate
Sign in to savePemafibrate, sold under the brand name Parmodia, is a peroxisome proliferator-activated receptor alpha (PPARα) agonist. It is developed and marketed by Kowa Pharmaceuticals.
Chemical data
- Formula
- C28H30N2O6
- Molecular weight
- 490.5 g/mol
- IUPAC name
- (2R)-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid
- SMILES
- CC[C@H](C(=O)O)OC1=CC=CC(=C1)CN(CCCOC2=CC=C(C=C2)OC)C3=NC4=CC=CC=C4O3
- InChIKey
- ZHKNLJLMDFQVHJ-RUZDIDTESA-N
- XLogP
- 6.2
- Polar surface area
- 94.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2017
- Admin. routes
- oral
- Indications
- cardiovascular disease, diabetic retinopathy
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 490.21
Show 4 more facts
- chemical formula
- C₂₈H₃₀N₂O₆
- canonical SMILES
- CCC(C(=O)O)OC1=CC=CC(=C1)CN(CCCOC2=CC=C(C=C2)OC)C3=NC4=CC=CC=C4O3
- isomeric SMILES
- CC[C@H](C(=O)O)OC1=CC=CC(=C1)CN(CCCOC2=CC=C(C=C2)OC)C3=NC4=CC=CC=C4O3
- Commons category
- Pemafibrate
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
{{Infobox drug | drug_name = | INN = | type = | IUPAC_name = (2R)-2-[3-({1,3-Benzoxazol-2-yl[3-(4-methoxyphenoxy)propyl]amino}methyl)phenoxy]butanoic acid | image = Pemafibrate.svg | image_class = skin-invert-image | width = | alt = | caption =
| pronounce = | tradename = Parmodia | Drugs.com = | MedlinePlus = | DailyMedID = | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = Oral | class = | ATCvet = | ATC_prefix = C10 | ATC_suffix = AB12 | ATC_supplemental =
Excerpted from Wikipedia’s “pemafibrate” article, available under the CC BY-SA 4.0 licence.