pempidine
Sign in to savePempidine is a nicotinic antagonist drug, first reported in 1958 by two research groups working independently, and introduced as an oral treatment for hypertension.
Chemical data
- Formula
- C10H21N
- Molecular weight
- 155.28 g/mol
- IUPAC name
- 1,2,2,6,6-pentamethylpiperidine
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- +155.167
Show 1 more fact
- P2868
- nicotinic antagonist
via Wikidata · CC0
Article
5 sectionsContents
- Pharmacology
- Toxicology
- Chemistry
- References
- External links
Pempidine is a nicotinic antagonist drug, first reported in 1958 by two research groups working independently, and introduced as an oral treatment for hypertension.
==Pharmacology== Reports on the "classical" pharmacology of pempidine have been published. The Spinks group, at ICI, compared pempidine, its N-ethyl analogue, and mecamylamine in considerable detail, with additional data related to several structurally simpler compounds.