PFN2
Sign in to saveAlso known as D3S1319E, PFL, profilin 2
Profilin-2 is a protein that in humans is encoded by the PFN2 gene.
Gene data
PFN2- Name
- profilin 2
- Type
- protein-coding
- Position
- 149,952,354–150,050,788 (−)
- Aliases
- D3S1319E, PFL
- Ensembl
- ENSG00000070087
- RefSeq RNA
- NM_002628.5, NM_053024.4
- RefSeq protein
- NP_002619.1, NP_444252.1
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
profilin 2
- Symbol
- PFN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:149,952,354-150,050,788
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PFN2 PDB 1d1j.png
Show 7 more facts
- HomoloGene ID
- 1974
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5217
- genomic end
- 149768575
- genomic start
- 149682691
- chromosome
- human chromosome 3
- cytogenetic location
- 3q25.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
Profilin-2 is a protein that in humans is encoded by the PFN2 gene.
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Excerpted from Wikipedia’s “PFN2” article, available under the CC BY-SA 4.0 licence.