Structure via PubChem · Public domain (PubChem)
phenylethylmalonamide
Sign in to saveAlso known as 2-Phenyl-2-ethylmalondiamide, PEMA
Phenylethylmalonamide (PEMA) is an active metabolite of the anticonvulsant drug primidone, although it is produced in a much lower concentration than phenobarbital, the other active metabolite.
In the Vinony graph
Vinony's link graph records 3 inbound references to phenylethylmalonamide, and connects out to chemical formula, organic compound and molar mass.
It is catalogued under topics including Carboxamides, Chembox image size set and ECHA InfoCard ID from Wikidata.
Vinony links it to 9 Wikipedia language editions.
Chemical data
- Formula
- C11H14N2O2
- Molecular weight
- 206.24 g/mol
- IUPAC name
- 2-ethyl-2-phenylpropanediamide
- SMILES
- CCC(C1=CC=CC=C1)(C(=O)N)C(=O)N
- InChIKey
- JFZHPFOXAAIUMB-UHFFFAOYSA-N
- XLogP
- 0.1
- Polar surface area
- 86.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
77 papers- Phenylethylmalonamide in essential tremor. A double-blind controlled study.Journal of neurology, neurosurgery, and psychiatry · 1981
- Clearance of phenylethylmalonamide during haemodialysis of a patient with renal failure.Therapeutic drug monitoring · 1990
- Serum concentrations of primidone and its metabolites, phenylethylmalonamide and phenobarbital, in the dog.American journal of veterinary research · 1980
- Pharmacokinetics of phenylethylmalonamide (PEMA) in elderly men.European journal of clinical pharmacology · 1987
- Phenylethylmalonamide (PEMA). An important metabolite of primidone.Archives of neurology · 1972
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 206.106
Show 2 more facts
- chemical formula
- C₁₁H₁₄N₂O₂
- canonical SMILES
- CCC(C1=CC=CC=C1)(C(=O)N)C(=O)N
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Phenylethylmalonamide (PEMA) is an active metabolite of the anticonvulsant drug primidone, although it is produced in a much lower concentration than phenobarbital, the other active metabolite.
==References==
Excerpted from Wikipedia’s “phenylethylmalonamide” article, available under the CC BY-SA 4.0 licence.