phenylethylmalonamide
Sign in to saveAlso known as 2-Phenyl-2-ethylmalondiamide, PEMA
Phenylethylmalonamide (PEMA) is an active metabolite of the anticonvulsant drug primidone, although it is produced in a much lower concentration than phenobarbital, the other active metabolite.
Research
77 papers- Phenylethylmalonamide in essential tremor. A double-blind controlled study.Journal of neurology, neurosurgery, and psychiatry · 1981
- Clearance of phenylethylmalonamide during haemodialysis of a patient with renal failure.Therapeutic drug monitoring · 1990
- Serum concentrations of primidone and its metabolites, phenylethylmalonamide and phenobarbital, in the dog.American journal of veterinary research · 1980
- Pharmacokinetics of phenylethylmalonamide (PEMA) in elderly men.European journal of clinical pharmacology · 1987
- Phenylethylmalonamide (PEMA). An important metabolite of primidone.Archives of neurology · 1972
via PubMed
Wikidata facts
- Mass
- 206.106
Show 2 more facts
- chemical formula
- C₁₁H₁₄N₂O₂
- canonical SMILES
- CCC(C1=CC=CC=C1)(C(=O)N)C(=O)N
Sources (2)
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Article
1 sectionsContents
- References
Phenylethylmalonamide (PEMA) is an active metabolite of the anticonvulsant drug primidone, although it is produced in a much lower concentration than phenobarbital, the other active metabolite.
==References==
Connections
chemical formula
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organic compound
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molar mass
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Q180686
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CAS Registry Number
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PubChem
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simplified molecular input line entry specification
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phenobarbital
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Q2311683
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International Chemical Identifier
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European Chemicals Agency
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standard state
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primidone
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Unique Ingredient Identifier
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Preferred IUPAC name
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