苯甲酰甲醛
Phenylglyoxal is the organic compound with the formula C6H5C(O)C(O)H. It contains both an aldehyde and a ketone functional group. It is yellow liquid when anhydrous but readily forms a colorless crystalline hydrate. It has been used as a reagent to modify the amino acid, arginine. It has also been used to attach chemical payload (probes) to the amino acid citrulline and to peptides/proteins.
Chemical data
- Formula
- C8H6O2
- Molecular weight
- 134.13 g/mol
- IUPAC name
- 2-oxo-2-phenylacetaldehyde
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,023 papers- Phenylglyoxal-based visualization of citrullinated proteins on Western blots.Molecules (Basel, Switzerland) · 2015
- Phenylglyoxal is not a selective inhibitor of phagocytosis.Journal of cell science · 1979
- Phenylglyoxal as a template site-specific reagent for DNA and RNA polymerases. Selective inhibition of initiation.The Journal of biological chemistry · 1980
- Phenylglyoxal modification of arginines in mammalian D-amino-acid oxidase.