فولکودین
Sign in to saveAlso known as 3-morpholinoethylmorphine, morpholinylethylmorphine, 3-(2-morpholinoethyl)morphine, beta-morpholinoethylmorphine, tetrahydro-1,4-oxazinylmethylcodeine, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-3-(2-morpholinoethoxy)morphinan-6-alpha-ol, 3-(2-(4-morpholinyl)ethyl)morphine
Pholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine.
Key facts
- Drug.image
- Pholcodine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Pholcodine3DanJ.gif
- Drug.width2
- 250
- Drug.tradename
- Logicin, others
- Drug.addiction_liability
- High
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- R05
- Drug.ATC_suffix
- DA08
- Drug.legal_BR
- A2
- Drug.legal_CA
- Schedule I
- Drug.legal_DE
- Anlage II
- Drug.legal_UK
- Class B
- Drug.legal_US
- Schedule I
- Drug.bioavailability
- Maximum plasma conc. attained 4-8 hours after oral dose.
- Drug.protein_bound
- 23.5%
- Drug.metabolism
- Liver
via Wikipedia infobox
Research
145 papers- Pholcodine.Journal of clinical pharmacy and therapeutics · 1988
- Pholcodine and allergy to neuromuscular blocking agents: where are we and how did we get here?British journal of anaesthesia · 2024
- Pholcodine exposure increases the risk of perioperative anaphylaxis to neuromuscular blocking agents: the ALPHO case-control study.British journal of anaesthesia · 2023
- Cough up, time's up: pholcodine and risk of anaphylaxis to general anaesthetics.Archives of disease in childhood · 2023
- Safety update: withdrawal of pholcodine-containing medicines.Drug and therapeutics bulletin · 2023
via PubMed