Structure via PubChem · Public domain (PubChem)
phosphocholine cation
Sign in to saveAlso known as Trimethyl(2-(phosphonooxy)ethyl)ammonium, ChoP, Phosphoryl-choline, O-phosphocholine, N-Trimethyl-2-aminoethylphosphonate, Choline phosphate, [2-(trimethylazaniumyl)ethoxy]phosphonic acid, Choline, dihydrogen phosphate (ester) (8CI)
Phosphocholine is an intermediate in the synthesis of phosphatidylcholine in tissues. Phosphocholine is made in a reaction, catalyzed by choline kinase, that converts ATP and choline into phosphocholine and ADP. Phosphocholine is a molecule found, for example, in lecithin.
Chemical data
- Formula
- C5H15NO4P+
- Molecular weight
- 184.15 g/mol
- IUPAC name
- trimethyl(2-phosphonooxyethyl)azanium
- SMILES
- C[N+](C)(C)CCOP(=O)(O)O
- InChIKey
- YHHSONZFOIEMCP-UHFFFAOYSA-O
- XLogP
- -1.5
- Polar surface area
- 66.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 1
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- cation
- Mass
- 184.074
Show 5 more facts
- found in taxon
- Caenorhabditis elegans
- subject has role
- primary metabolite
- canonical SMILES
- C[N+](C)(C)CCOP(=O)(O)O
- Commons category
- Phosphocholine
- chemical formula
- C₅H₁₅NO₄P⁺
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Phosphocholine is an intermediate in the synthesis of phosphatidylcholine in tissues. Phosphocholine is made in a reaction, catalyzed by choline kinase, that converts ATP and choline into phosphocholine and ADP. Phosphocholine is a molecule found, for example, in lecithin.
In nematodes and human placentas, phosphocholine is selectively attached to other proteins as a posttranslational modification to suppress an immune response by their hosts.
Excerpted from Wikipedia’s “phosphocholine cation” article, available under the CC BY-SA 4.0 licence.