phosphatidyl serine
Also known as distearoylphosphatidylserine, PS, Ptd-L-Ser, phosphatidyl-L-serine, phosphatidylserine, Phosphatidylserine, Phosphatidyl-L-serine
Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is a phospholipid and is a component of the cell membrane. It plays a key role in cell cycle signaling, specifically in relation to apoptosis. It is a key pathway for viruses to enter cells via apoptotic mimicry. Its exposure on the outer surface of a membrane marks the cell for destruction via apoptosis.
Research
10,353 papers- Phosphatidyl serine.The Journal of biological chemistry · 1955
- The distribution and function of phosphatidylserine in cellular membranes.Annual review of biophysics · 2010
- Role of phosphatidyl-serine in bone repair and its technological exploitation.Molecules (Basel, Switzerland) · 2009
- Phosphatidylserine.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 1999
- Cerebrovascular events in patients with isolated anti-phosphatidyl-serine/prothrombin antibodies.Immunologic research · 2021
via PubMed
Article
13 sectionsContents
- Structure
- Biosynthesis
- Composition
- Functions
- Cognitive function
- Apoptosis
- Dietary sources
- Supplementation
- Health claims
- Cognition
- Safety
- References
- External links
Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is a phospholipid and is a component of the cell membrane. It plays a key role in cell cycle signaling, specifically in relation to apoptosis. It is a key pathway for viruses to enter cells via apoptotic mimicry. Its exposure on the outer surface of a membrane marks the cell for destruction via apoptosis.
== Structure == Phosphatidylserine is a phospholipid—more specifically a glycerophospholipid—which consists of two fatty acids attached in ester linkage to the first and second carbon of glycerol and serine attached through a phosphodiester linkage to the third carbon of the glycerol.