پلکوناریل
Sign in to saveAlso known as Pleconaril
Pleconaril (Picovir) is an antiviral drug that was being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in patients exposed to picornavirus respiratory infections. Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus. It has shown useful activity against the dangerous enterovirus D68.
Research
208 papers- The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants.Antiviral research · 2024
- Pleconaril, a novel antipicornaviral agent.Pharmacotherapy · 2003
- Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial.Nature medicine · 2023
- Pleconaril Sanofi Synthélabo/ViroPharma.Current opinion in investigational drugs (London, England : 2000) · 2000
- Clinical characteristics of severe neonatal enterovirus infection: a systematic review.BMC pediatrics · 2021
via PubMed
Wikidata facts
- Mass
- 381.13
Show 4 more facts
- found in taxon
- Isatis tinctoria
- Commons category
- Pleconaril
- chemical formula
- C₁₈H₁₈F₃N₃O₃
- canonical SMILES
- CC1=CC(=CC(=C1OCCCC2=CC(=NO2)C)C)C3=NOC(=N3)C(F)(F)F
Sources (2)
via Wikidata · CC0