pleconaril
Sign in to savePleconaril (Picovir) is an antiviral drug that was being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in patients exposed to picornavirus respiratory infections. Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus. It has shown useful activity against the dangerous enterovirus D68.
Research
208 papers- The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants.Antiviral research · 2024
- Pleconaril, a novel antipicornaviral agent.Pharmacotherapy · 2003
- Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial.Nature medicine · 2023
- Pleconaril Sanofi Synthélabo/ViroPharma.Current opinion in investigational drugs (London, England : 2000) · 2000
- Clinical characteristics of severe neonatal enterovirus infection: a systematic review.BMC pediatrics · 2021
via PubMed
~2 min read
Encyclopedic overview
7 sectionsContents
- History
- Mechanism of action
- Clinical trials
- Resistance
- Side effects
- See also
- References
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| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = ? | routes_of_administration = Oral, intranasal
Excerpted from Wikipedia’s “pleconaril” article, available under the CC BY-SA 4.0 licence.