Structure via PubChem · Public domain (PubChem)
polygodial
Sign in to saveAlso known as (-)-polygodial, poligodial, tadeonal
Polygodial a is chemical compound found in dorrigo pepper, mountain pepper, horopito, canelo, paracress, water-pepper, and Dendrodoris limbata.
Chemical data
- Formula
- C15H22O2
- Molecular weight
- 234.33 g/mol
- IUPAC name
- (1R,4aS,8aS)-5,5,8a-trimethyl-1,4,4a,6,7,8-hexahydronaphthalene-1,2-dicarbaldehyde
- SMILES
- C[C@]12CCCC([C@@H]1CC=C([C@@H]2C=O)C=O)(C)C
- InChIKey
- AZJUJOFIHHNCSV-KCQAQPDRSA-N
- XLogP
- 3.2
- Polar surface area
- 34.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
166 papers- Polygodial, a drimane sesquiterpenoid dialdehyde purified from Drimys winteri, inhibits voltage-gated sodium channels.Natural product research · 2022
- Sesquiterpene Polygodial from Drimys brasiliensis (Winteraceae) Down-Regulates Implant-Induced Inflammation and Fibrogenesis in Mice.Journal of natural products · 2020
- Antifungal mechanism of polygodial.Journal of agricultural and food chemistry · 2001
- Polygodial, an antifungal potentiator.Journal of natural products · 1988
- Polygodial, a Sesquiterpene Dialdehyde, Activates Apoptotic Signaling in Castration-Resistant Prostate Cancer Cell Lines by Inducing Oxidative Stress.Cancers · 2022
via PubMed
Wikidata facts
- Subclass of
- aldehydes
- Mass
- 234.162
Show 5 more facts
- found in taxon
- Persicaria hydropiper
- chemical formula
- C₁₅H₂₂O₂
- isomeric SMILES
- C[C@]12CCCC([C@@H]1CC=C([C@@H]2C=O)C=O)(C)C
- canonical SMILES
- CC1(CCCC2(C1CC=C(C2C=O)C=O)C)C
- subject has role
- antifungal
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- Biological activity
- References
Polygodial a is chemical compound found in dorrigo pepper, mountain pepper, horopito, canelo, paracress, water-pepper, and Dendrodoris limbata. It is a drimane-type sesquiterpene dialdehyde with the chemical formula C15H22O2.
Polygodial elicits a warm and pungent flavour. The compound activates the TRPA1 pain receptor in nerve endings in the mouth that mediate the sensation of pungency.
Excerpted from Wikipedia’s “polygodial” article, available under the CC BY-SA 4.0 licence.