Structure via PubChem · Public domain (PubChem)
povidone-iodine
Sign in to saveAlso known as E-Z Prep 220, E-Z Scrub 201, Betadine, E-Z Scrub 241, E-Z Prep, E-Z scrub, povidone iodine, PVP-I
Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. It may also be used for minor wounds. It may be applied to the skin as a liquid, an ointment or a powder.
OverviewAI-generated
Povidone-iodine is a chemical compound with the formula C₆H₉I₂NO. Its IUPAC name is 1-ethenylpyrrolidin-2-one;molecular iodine. The substance has a mass of 364.87736 and a weight of 364.95. It possesses a charge of 0, one hydrogen bond acceptor, and zero hydrogen bond donors. The topological polar surface area is 20.3.
The defined daily dose for povidone-iodine is 0.2. The compound is associated with 5880 entries in the PubMed database. It is referenced by 297 other encyclopedia articles.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C6H9I2NO
- Molecular weight
- 364.95 g/mol
- IUPAC name
- 1-ethenylpyrrolidin-2-one;molecular iodine
- SMILES
- C=CN1CCCC1=O.II
- InChIKey
- CPKVUHPKYQGHMW-UHFFFAOYSA-N
- Polar surface area
- 20.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Unknown
- First approval
- 1985
- Admin. routes
- topical
- Indications
- infection, acne, pneumonia, dental caries
via ChEMBL · EBI
Research
5,880 papers- Povidone-iodine concentration and dosing in cataract surgery.Survey of ophthalmology · 2018
- Repurposing povidone-iodine to reduce the risk of SARS-CoV-2 infection and transmission: a narrative review.Annals of medicine · 2022
- Povidone iodine.British dental journal · 2020
- Povidone iodine development.British dental journal · 2020
- Povidone-iodine: use in hand disinfection, skin preparation and antiseptic irrigation.International wound journal · 2008
via PubMed
Wikidata facts
- Subclass of
- ionomer
- Has part
- triiodide ion
- Mass
- 364.87736
- Has use
- medication
Show 6 more facts
- chemical formula
- C₆H₉I₂NO
- canonical SMILES
- C=CN1CCCC1=O.II
- Commons category
- Povidone-iodine
- defined daily dose
- 0.2
- NCI Thesaurus ID
- C766
- different from
- polyvinylpyrrolidone
Sources (3)
via Wikidata · CC0
~8 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Eyes
- Pleurodesis
- Vagina
- Alternatives
- Contraindications
- Side effects
- Interactions
- Structure
- History
- Research
- References
- Further reading
Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. It may also be used for minor wounds. It may be applied to the skin as a liquid, an ointment or a powder.
Side effects include skin irritation and sometimes swelling. If used on large wounds, kidney problems, high blood sodium, and metabolic acidosis may occur. It is not recommended in women who are less than 32 weeks pregnant. Frequent use is not recommended in people with thyroid problems or who are taking lithium.
Excerpted from Wikipedia’s “povidone-iodine” article, available under the CC BY-SA 4.0 licence.