Structure via PubChem · Public domain (PubChem)
پردنیموستین
Sign in to savePrednimustine, sold under the brand names Mostarina and Sterecyst, is a medication which is used in chemotherapy in the treatment of leukemias and lymphomas. It is the ester formed from two other drugs, prednisolone and chlorambucil. Rarely, it has been associated with myoclonus.
Chemical data
- Formula
- C35H45Cl2NO6
- Molecular weight
- 646.6 g/mol
- IUPAC name
- [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- lymphoma, neoplasm
via ChEMBL · EBI
Research
189 papers- Prednimustine.IARC monographs on the evaluation of carcinogenic risks to humans · 1990
- Prednimustine.Seminars in oncology · 1986
- Prednimustine in advanced breast cancer: a review.Seminars in oncology · 1986
- [Myoclonus induced by prednimustine].Neurologia (Barcelona, Spain) · 1998
- Prednimustine treatment in malignant lymphomas.Oncology · 1989
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