PRLR
Sign in to saveAlso known as HPRL, RI-PRLR, prolactin receptor, MFAB, hPRLrI, Prolactin receptor, IPR033230
gen van de soort Homo sapiens
In the Vinony graph
Within Vinony's link graph, PRLR is referenced by 217 other articles, and connects out to thyrotropin-releasing hormone, prolactin and growth hormone.
It sits within the topics Genes on human chromosome 5 and Protein pages needing a picture.
Its subject is documented across 6 Wikipedia language editions.
Gene data
PRLR- Name
- prolactin receptor
- Type
- protein-coding
- Position
- 35,048,756–35,230,678 (−)
- Aliases
- HPRL, MFAB, RI-PRLR, hPRLrI
- Ensembl
- ENSG00000113494
- RefSeq RNA
- NM_000949.7, NM_001204314.2, NM_001204315.1, NM_001204316.1, NM_001204317.1
- RefSeq protein
- NP_000940.1, NP_001191243.1, NP_001191244.1, NP_001191245.1, NP_001191246.1
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
prolactin receptor
- Symbol
- PRLR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:35,048,756-35,230,678
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Subclass of
- cytokine receptor
Show 10 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 733
- exact match
- identifiers.org/ncbigene/5618
- genomic end
- 35230487
- genomic start
- 35048861
- chromosome
- human chromosome 5
- cytogenetic location
- 5p13.2
- genetic association
- hyperprolactinemia
- Commons category
- Prolactin receptor
via Wikidata · CC0