risperidone

Also known as R-64-766, R-64766

thumb|A box of Rispolept (Risperidone) tablets Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder, as well as aggressive and self-injurious behaviors associated with autism spectrum disorder. It is taken either by mouth or by injection (i.e., subcutaneous or intramuscular). The injectable versions are long-acting and last for 2–4 weeks.

Chemical data

Formula: C23H27FN4O2
Molecular weight: 410.5 g/mol
IUPAC name: 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
InChIKey: RAPZEAPATHNIPO-UHFFFAOYSA-N
XLogP: 2.7
Polar surface area: 61.9 Å²
H-bond donors: 0
H-bond acceptors: 6
Formal charge: 0

via PubChem

Research

12,316 papers

Risperidone.Profiles of drug substances, excipients, and related methodology · 2012
Risperidone In Situ Microparticles: A Review in Schizophrenia.Drugs · 2025
[Risperidone].Deutsche medizinische Wochenschrift (1946) · 2003
Neuropharmacological effect of risperidone: From chemistry to medicine.Chemico-biological interactions · 2023
Classics in Chemical Neuroscience: Risperidone.ACS chemical neuroscience · 2018

via PubMed

Wikidata facts

Mass: 410.211804

Show 6 more facts

Commons category: Risperidone
chemical formula: C₂₃H₂₇FN₄O₂
canonical SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
World Health Organisation international non-proprietary name: risperidone
defined daily dose: 5
stylized name: RisperDAL

Sources (9)

via Wikidata · CC0

~17 min read

Article

21 sections

Contents

Medical uses
Schizophrenia
Bipolar disorder
Autism
Dementia
Other uses
Available forms
Adverse effects
Discontinuation
Dementia
Interactions
Pharmacology
Pharmacodynamics
Pharmacokinetics
Society and culture
Legal status
Lawsuits
Brand names
References
Further reading
External links

thumb|A box of Rispolept (Risperidone) tablets

Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder, as well as aggressive and self-injurious behaviors associated with autism spectrum disorder. It is taken either by mouth or by injection (i.e., subcutaneous or intramuscular). The injectable versions are long-acting and last for 2–4 weeks.