Structure via PubChem · Public domain (PubChem)
risperidone
Sign in to saveAlso known as R-64-766, R-64766
thumb|A box of Rispolept (Risperidone) tablets Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder, as well as aggressive and self-injurious behaviors associated with autism spectrum disorder. It is taken either by mouth or by injection (i.e., subcutaneous or intramuscular). The injectable versions are long-acting and last for 2–4 weeks.
OverviewAI-generated
Risperidone is a chemical compound with the formula C₂₃H₂₇FN₄O₂. Its IUPAC name is 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one. The molecule has a mass of 410.211804 and a weight of 410.5. It is characterized by a charge of 0, an xlogp of 2.7, and a topological polar surface area of 61.9. The compound has no hydrogen bond donors and six hydrogen bond acceptors.
The defined daily dose for risperidone is 5. It is also referred to by the stylized names "risperiDONE" and "RisperDAL". A search for risperidone in PubMed yields 12,316 results. The subject is referenced by 3,655 other encyclopedia articles.
Synthesized by Vinony from 19 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C23H27FN4O2
- Molecular weight
- 410.5 g/mol
- IUPAC name
- 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
- SMILES
- CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
- InChIKey
- RAPZEAPATHNIPO-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 61.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
12,316 papers- Risperidone.Profiles of drug substances, excipients, and related methodology · 2012
- Risperidone In Situ Microparticles: A Review in Schizophrenia.Drugs · 2025
- [Risperidone].Deutsche medizinische Wochenschrift (1946) · 2003
- Neuropharmacological effect of risperidone: From chemistry to medicine.Chemico-biological interactions · 2023
- Classics in Chemical Neuroscience: Risperidone.ACS chemical neuroscience · 2018
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- carbon
- Mass
- 410.211804
- Has use
- medication
Show 11 more facts
- Commons category
- Risperidone
- medical condition treated
- autism
- chemical formula
- C₂₃H₂₇FN₄O₂
- canonical SMILES
- CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
- World Health Organisation international non-proprietary name
- risperidone
- subject has role
- essential medicine
- defined daily dose
- 5
- physically interacts with
- Histamine receptor H1
- legal status (medicine)
- boxed warning
- stylized name
- RisperDAL
- significant drug interaction
- fluoxetine
Sources (9)
via Wikidata · CC0
~17 min read
Encyclopedic overview
21 sectionsContents
- Medical uses
- Schizophrenia
- Bipolar disorder
- Autism
- Dementia
- Other uses
- Available forms
- Adverse effects
- Discontinuation
- Dementia
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Society and culture
- Legal status
- Lawsuits
- Brand names
- References
- Further reading
- External links
thumb|A box of Rispolept (Risperidone) tablets
Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder, as well as aggressive and self-injurious behaviors associated with autism spectrum disorder. It is taken either by mouth or by injection (i.e., subcutaneous or intramuscular). The injectable versions are long-acting and last for 2–4 weeks.
Excerpted from Wikipedia’s “risperidone” article, available under the CC BY-SA 4.0 licence.