Proglumetacin (usually supplied as the maleate salt) is a nonsteroidal anti-inflammatory drug (NSAID). It is a codrug (that is, a mutual prodrug) of indometacin and proglumide. After oral intake, it is absorbed and metabolized to indometacin and proglumide. These two substances are then released into the system in a 1:1 molar ratio.
via PubMed
{{Infobox drug | Watchedfields = changed | verifiedrevid = 443950501 | IUPAC_name = 3-{4-[2-({[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)ethyl]piperazin-1-yl}propyl N2-benzoyl-N,N-dipropyl-α-glutaminate | image = Proglumetacin.svg | image_class = skin-invert-image | caption = Structure of proglumetacin | imageL = Indometacin.svg | imageR = Proglumide_structure.svg | image_classL = skin-invert-image | image_classR = skin-invert-image | captionLR = Structures of the two metabolites
| tradename = Afloxan, Protaxon, Proxil | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).