Also known as CD155, HVED, NECL5, Necl-5, PVS, TAGE4, poliovirus receptor, PVR cell adhesion molecule
gen de la especie Homo sapiens
Gene data
PVR- Name
- PVR cell adhesion molecule
- Type
- protein-coding
- Position
- 44,643,798–44,666,162 (+)
- Aliases
- CD155, HVED, NECL5, Necl-5, PVS, TAGE4
- Ensembl
- ENSG00000073008
- RefSeq RNA
- NM_001135768.3, NM_001135769.3, NM_001135770.4, NM_006505.5
- RefSeq protein
- NP_001129240.1, NP_001129241.1, NP_001129242.2, NP_006496.4
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
PVR cell adhesion molecule
- Symbol
- PVR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:44,643,798-44,666,162
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Poliovirus binding receptor 1DGI.png
Show 8 more facts
- HomoloGene ID
- 9672
- genetic association
- multiple sclerosis
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5817
- genomic end
- 44666162
- genomic start
- 45147098
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.31
via Wikidata · CC0