Structure via PubChem · Public domain (PubChem)
raltegravir
Sign in to saveAlso known as MK-0518, RAL
Raltegravir, sold under the brand name Isentress, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. It may also be used, as part of post-exposure prophylaxis, to prevent HIV infection following potential exposure. It is taken by mouth.
Chemical data
- Formula
- C20H21FN6O5
- Molecular weight
- 444.4 g/mol
- IUPAC name
- N-[2-[4-[(4-fluorophenyl)methylcarbamoyl]-5-hydroxy-1-methyl-6-oxopyrimidin-2-yl]propan-2-yl]-5-methyl-1,3,4-oxadiazole-2-carboxamide
- SMILES
- CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)NCC3=CC=C(C=C3)F
- InChIKey
- CZFFBEXEKNGXKS-UHFFFAOYSA-N
- XLogP
- 1.1
- Polar surface area
- 150 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Formal charge
- 0
via PubChem
~8 min read
Encyclopedic overview
9 sectionsContents
- Medical uses
- Efficacy
- Side effects
- Mechanism of action
- Chemistry
- History
- Research
- References
- External links
{{Drugbox | image = Raltegravir structure.svg | image_class = skin-invert-image | width = 290 | alt = 2 | image2 = Raltegravir-3D-balls.png | image_class2 = bg-transparent | width2 = 290 | alt2 =
| pronounce = | tradename = Isentress | Drugs.com = | MedlinePlus = a608004 | DailyMedID = Raltegravir | pregnancy_AU = B3 | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = By mouth | ATC_prefix = J05 | ATC_suffix = AJ01
Excerpted from Wikipedia’s “raltegravir” article, available under the CC BY-SA 4.0 licence.