File:Losartan_structure.svg · Wikimedia Commons · See Wikimedia Commons
Also known as DuP 753, MK-954, 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole, (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol, DuP 89
Losartan, sold under the brand name Cozaar among others, is a medication used to treat high blood pressure (hypertension). It is in the angiotensin receptor blocker (ARB) family of medication, and is considered protective of the kidneys. Besides hypertension, it is also used in diabetic kidney disease, heart failure, and left ventricular enlargement. It comes as a tablet that is taken by mouth. It may be used alone or in addition to other blood pressure medication. Up to six weeks may be required for the full effects to occur.
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{{Infobox drug | verifiedrevid = 458612349 | image = Losartan structure.svg | image_class = skin-invert-image | alt = Skeletal formula | width = 200 | image2 = Losartan-from-xtal-3D-bs-17.png | image_class2 = bg-transparent | alt2 = Ball-and-stick model | width2 = | caption =
| pronounce = | tradename = Cozaar, others | Drugs.com = | MedlinePlus = a695008 | DailyMedID = Losartan | pregnancy_AU = D | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = By mouth | class = Angiotensin II receptor antagonist | ATC_prefix = C09 | ATC_suffix = CA01 | ATC_supplemental =
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).