rimantadine
Rimantadine (INN, sold under the trade name Flumadine) is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection. When taken within one to two days of developing symptoms, rimantadine can shorten the duration and moderate the severity of influenza. Rimantadine can mitigate symptoms, including fever. Both rimantadine and the similar drug amantadine are derivates of adamantane. Rimantadine is found to be more effective than amantadine because when used the patient displays fewer symptoms. Rimantadine was approved by the Food and Drug Administra
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464382566
- Drug.IUPAC_name
- 1-(adamantanyl)ethanamine
- Drug.image
- Rimantadine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 125
- Drug.image2
- Rimantadine ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 150
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Flumadine
- Drug.MedlinePlus
- a698029
- Drug.pregnancy_category
Article
16 sectionsContents
- Medical uses
- Influenza A
- Influenza resistance
- Rimantadine enantiomers interactions with M2
- Parkinson's disease
- Others
- Side effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Chemistry
- Synthesis
- History
- See also
- References
- External links
Rimantadine (INN, sold under the trade name Flumadine) is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection. When taken within one to two days of developing symptoms, rimantadine can shorten the duration and moderate the severity of influenza. Rimantadine can mitigate symptoms, including fever. Both rimantadine and the similar drug amantadine are derivates of adamantane. Rimantadine is found to be more effective than amantadine because when used the patient displays fewer symptoms. Rimantadine was approved by the Food and Drug Administration (FDA) in 1994.
Rimantadine was approved for medical use in 1993. Seasonal H3N2 and 2009 pandemic flu samples tested have shown resistance to rimantadine, and it is no longer recommended to prescribe for treatment of the flu.