Structure via PubChem · Public domain (PubChem)
ritodrine
Sign in to saveRitodrine, formerly sold under the brand name Yutopar among others, is a tocolytic drug used to stop premature labor. It was withdrawn from the US market, according to the FDA Orange Book. It was available in oral tablets or as an injection and was typically used as the hydrochloride salt.
Chemical data
- Formula
- C17H21NO3
- Molecular weight
- 287.35 g/mol
- IUPAC name
- 4-[2-[[(1R,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol
- SMILES
- C[C@@H]([C@@H](C1=CC=C(C=C1)O)O)NCCC2=CC=C(C=C2)O
- InChIKey
- IOVGROKTTNBUGK-SJCJKPOMSA-N
- XLogP
- 2.3
- Polar surface area
- 72.7 Ų
- H-bond donors
- 4
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,278 papers- Ritodrine-induced rhabdomyolysis and psychiatric symptoms: a case report and literature review.BMC pregnancy and childbirth · 2023
- Ritodrine versus salbutamol for external cephalic version.Minerva obstetrics and gynecology · 2022
- Ritodrine pharmacokinetics.Clinical pharmacology and therapeutics · 1986
- Ritodrine in the treatment of preterm labour: a meta-analysis.The Indian journal of medical research · 2005
- Ritodrine, reexamined.MCN. The American journal of maternal child nursing · 1993
via PubMed
Wikidata facts
- Mass
- 287.152144
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₇H₂₁NO₃
- canonical SMILES
- CC(C(C1=CC=C(C=C1)O)O)NCCC2=CC=C(C=C2)O
- isomeric SMILES
- C[C@@H]([C@@H](C1=CC=C(C=C1)O)O)NCCC2=CC=C(C=C2)O
- subject has role
- tocolytic uterine relaxants
- Commons category
- Ritodrine
- defined daily dose
- 40
Sources (3)
via Wikidata · CC0
~3 min read
Encyclopedic overview
12 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Names
- See also
- References
Ritodrine, formerly sold under the brand name Yutopar among others, is a tocolytic drug used to stop premature labor. It was withdrawn from the US market, according to the FDA Orange Book. It was available in oral tablets or as an injection and was typically used as the hydrochloride salt.
The drug acts as a selective β2-adrenergic receptor agonist.
Excerpted from Wikipedia’s “ritodrine” article, available under the CC BY-SA 4.0 licence.
Available in 11 languages
via Wikidata sitelinks · CC0