Structure via PubChem · Public domain (PubChem)
(RS)-fenoprofen
Sign in to saveAlso known as 2-(m-phenoxyphenyl)propionic acid, alpha-(m-phenoxyphenyl)propionic acid, (+-)-m-phenoxyhydratropic acid, (+-)-2-(3-phenoxyphenyl)propionic acid, alpha-methyl-3-phenoxybenzeneacetic acid, 2-(3-phenoxyphenyl)propionic acid, (+/-)-fenoprofen, DL-2-(3-phenoxyphenyl)propionic acid
Fenoprofen, sold under the brand name Nalfon among others, is a nonsteroidal anti-inflammatory drug (NSAID). Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain. It has also been used to treat postoperative pain. It is available as a generic medication.
Chemical data
- Formula
- C15H14O3
- Molecular weight
- 242.27 g/mol
- IUPAC name
- 2-(3-phenoxyphenyl)propanoic acid
- SMILES
- CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)O
- InChIKey
- RDJGLLICXDHJDY-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
11 papers- Stereoselective inversion of (R)-fenoprofen to (S)-fenoprofen in humans.Journal of pharmaceutical sciences · 1985
- In vitro enantioselective glucuronidation of fenoprofen.Pharmacology · 1991
- Enantioseparation of six profenoid drugs by capillary electrophoresis with bovine serum albumin-modified gold nanoparticles as quasi-stationary phases.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2024
- Enantiospecific high-performance liquid chromatographic analysis of 2-phenylpropionic acid, ketoprofen and fenoprofen.Journal of chromatography · 1986
- Dataset of the first report of pharmacogenomics profiling in an outpatient spine setting.Data in brief · 2021
via PubMed
Wikidata facts
- Mass
- 242.094294
- Has use
- medication
Show 10 more facts
- chemical formula
- C₁₅H₁₄O₃
- medical condition treated
- osteoarthritis
- World Health Organisation international non-proprietary name
- fenoprofen
- canonical SMILES
- CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)O
- defined daily dose
- 1.2
- subject has role
- non-steroidal anti-inflammatory drug
- physically interacts with
- Prostaglandin-endoperoxide synthase 1
- Commons category
- Fenoprofen
- significant drug interaction
- tacrolimus
- legal status (medicine)
- boxed warning
Sources (7)
via Wikidata · CC0
~3 min read
Encyclopedic overview
10 sectionsContents
- Pharmacology
- Chirality and biological activity
- Contraindications
- Adverse effects
- Drug interactions
- Laboratory test interactions
- Brand names
- See also
- References
- External links
Fenoprofen, sold under the brand name Nalfon among others, is a nonsteroidal anti-inflammatory drug (NSAID). Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain. It has also been used to treat postoperative pain. It is available as a generic medication.
==Pharmacology== Decreases inflammation, pain, and fever, probably through inhibition of cyclooxygenase (COX-2 inhibitor) activity and prostaglandin synthesis.
Excerpted from Wikipedia’s “(RS)-fenoprofen” article, available under the CC BY-SA 4.0 licence.