(RS)-propylamphetamine
Sign in to savePropylamphetamine (code name PAL-424; also known as '''N-propylamphetamine or NPA''') is a psychostimulant of the amphetamine family which was never marketed. It was first developed in the 1970s, mainly for research into the metabolism of, and as a comparison tool to, other amphetamines.
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Propylamphetamine (code name PAL-424; also known as '''N-propylamphetamine or NPA') is a psychostimulant of the amphetamine family which was never marketed. It was first developed in the 1970s, mainly for research into the metabolism of, and as a comparison tool to, other amphetamines.
Propylamphetamine is inactive as a dopamine releasing agent in vitro and instead acts as a low-potency dopamine reuptake inhibitor with an of 1,013nM. The drug can be N-dealkylated to form amphetamine (10–20% excreted in urine after 24hours). A study in rats found propylamphetamine to be approximately 4-fold less potent than amphetamine.
Excerpted from Wikipedia’s “(RS)-propylamphetamine” article, available under the CC BY-SA 4.0 licence.