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salsalate

Structure via PubChem · Public domain (PubChem)

EntityQ1320691· pop 18· linked from 500 articles

Also known as Disalcid, 2-Carboxyphenyl salicylate, Sasapyrin, Sasapyrine, Salicyloxysalicylic acid, Disalicylsaeure, O-Salicylsalicylic acid, O-Salicylcylsalicylsaeure

Salsalate is a medication that belongs to the salicylate and nonsteroidal anti-inflammatory drug (NSAID) classes.

Key facts

Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
437202892
Drug.IUPAC_name
2-(2-Hydroxybenzoyl)oxybenzoic acid
Drug.image
Salsalate.svg
Drug.image_class
skin-invert-image
Drug.tradename
Disalcid, Salflex
Drug.MedlinePlus
a682880
Drug.pregnancy_US
C
Drug.legal_US
Rx-only
Drug.CAS_number
552-94-3
Drug.ATC_prefix
N02
Drug.ATC_suffix
BA06
Drug.PubChem
5161
Drug.DrugBank
DB01399
Drug.ChEBI
9014
Drug.ChemSpiderID
4977
Drug.UNII
V9MO595C9I

via Wikipedia infobox

Chemical data

Formula
C14H10O5
Molecular weight
258.23 g/mol
IUPAC name
2-(2-hydroxybenzoyl)oxybenzoic acid
SMILES
C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O
InChIKey
WVYADZUPLLSGPU-UHFFFAOYSA-N
XLogP
3
Polar surface area
83.8 Ų
H-bond donors
2
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
Fever, pain, obesity, atherosclerosis

via ChEMBL · EBI

Wikidata facts

Subclass of
depside
Mass
258.052823
Has use
medication
Show 10 more facts
chemical formula
C₁₄H₁₀O₅
medical condition treated
arthritis
canonical SMILES
C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O
defined daily dose
3
World Health Organisation international non-proprietary name
salsalate
Commons category
Salsalate
melting point
135
has characteristic
bitterness
legal status (medicine)
boxed warning
Sources (4)

via Wikidata · CC0

~2 min read

Encyclopedic overview

7 sections
Contents
  • Mechanism of action
  • Medical uses
  • Safety
  • Research
  • History
  • Synthesis
  • References

Salsalate is a medication that belongs to the salicylate and nonsteroidal anti-inflammatory drug (NSAID) classes.

Salsalate is the generic name of a prescription drug marketed under the brandnames Mono-Gesic, Salflex, Disalcid, and Salsitab. Other generic and brand name formulations may be available.

Excerpted from Wikipedia’s “salsalate” article, available under the CC BY-SA 4.0 licence.

Gallery (2)