Seliciclib (roscovitine or CYC202) is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors that inhibit multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase or state within the cell cycle of treated cells. Seliciclib is being developed by Cyclacel.
{{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 377431079 | ImageFile = Seliciclib structure.svg | ImageClass = skin-invert-image | PIN = (2R)-2-{[6-(Benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol | OtherNames = Roscovitine; CYC202
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).