silodosin
Sign in to saveAlso known as KMD-3213, Rapaflo®, Silodyx®, Rapilif, Urief, KAD 3213, KMD 3213
Silodosin, sold under the brand name Urief among others, is a medication used for the symptomatic treatment of benign prostatic hyperplasia. It acts as an alpha-1 adrenergic receptor antagonist.
Key facts
- Drug.MedlinePlus
- a609002
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464390579
- Drug.image
- Silodosin Structural Formula V.1.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Urief, others
- Drug.routes_of_administration
- By mouth
- Drug.class
- α1 blocker
- Drug.ATC_prefix
- G04
- Drug.ATC_suffix
- CA04
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.bioavailability
- 32%
- Drug.protein_bound
- 96.6%
via Wikipedia infobox
Research
587 papers- Silodosin.2012
- Silodosin: An Update on Efficacy, Safety and Clinical Indications in Urology.Advances in therapy · 2019
- Does Silodosin Improve Primary Ureteroscopy Access and Outcomes: Meta-Analysis of Randomized Controlled Trials.Journal of endourology · 2024
- Focus on Silodosin: Pros and Cons of Uroselectivity.Research and reports in urology · 2020
- Silodosin as a medical expulsive therapy for distal ureteral stones: A systematic review and meta-analysis.Indian journal of urology : IJU : journal of the Urological Society of India · 2023
via PubMed
Wikidata facts
- Mass
- 495.234491
Show 5 more facts
- Commons category
- Silodosin
- chemical formula
- C₂₅H₃₂F₃N₃O₄
- isomeric SMILES
- C[C@H](CC1=CC2=C(C(=C1)C(=O)N)N(CC2)CCCO)NCCOC3=CC=CC=C3OCC(F)(F)F
- canonical SMILES
- CC(CC1=CC2=C(C(=C1)C(=O)N)N(CC2)CCCO)NCCOC3=CC=CC=C3OCC(F)(F)F
- defined daily dose
- 8
via Wikidata · CC0
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Article
13 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- History
- Society and culture
- Brand names
- Research
- References
- Further reading
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464390579 | image = Silodosin Structural Formula V.1.svg | image_class = skin-invert-image | width = | alt = | caption =
| pronounce = | tradename = Urief, others | Drugs.com = | MedlinePlus = a609002 | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = α1 blocker | ATC_prefix = G04 | ATC_suffix = CA04 | ATC_supplemental =
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