SLC1A3
Sign in to saveAlso known as EA6, EAAT1, GLAST, GLAST1, solute carrier family 1 member 3
protein-coding gene in the species Homo sapiens
Gene data
SLC1A3- Name
- solute carrier family 1 member 3
- Type
- protein-coding
- Position
- 36,596,588–36,688,335 (+)
- Aliases
- EA6, EAAT1, GLAST, GLAST1
- Ensembl
- ENSG00000079215
- RefSeq RNA
- NM_001166695.3, NM_001166696.3, NM_001289939.2, NM_001289940.2, NM_001438454.1
- RefSeq protein
- NP_001160167.1, NP_001160168.1, NP_001276868.1, NP_001276869.1, NP_001425383.1
This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2014].
Gene Ontology
Biological process
Molecular function
L-glutamate transmembrane transporter activityL-glutamate transmembrane transporter activityL-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityprotein binding
Pathways
Synaptic vesicle cycle - Homo sapiens (human)Glutamatergic synapse - Homo sapiens (human)Huntington disease - Homo sapiens (human)Neurotransmitter release cycleNeurotransmitter uptake and metabolism In glial cellsTransmission across Chemical SynapsesNeuronal SystemDiseaseAstrocytic Glutamate-Glutamine Uptake And MetabolismGlutamate Neurotransmitter Release Cycle
via MyGene.info
Gene · Ensembl
solute carrier family 1 member 3
- Symbol
- SLC1A3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:36,596,584-36,688,335
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 6 more facts
- HomoloGene ID
- 20882
- exact match
- identifiers.org/ncbigene/6507
- genomic start
- 36596588
- genomic end
- 36688436
- cytogenetic location
- 5p13.2
- Commons category
- Excitatory amino acid transporter 1
Sources (8)
via Wikidata · CC0
Connections
glutamate transporter
Entity
mitochondrion
Entity
Q180686
Entity
DL-glutamic acid
Entity
aspartate transaminase
Entity
Ensembl genome database project
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transmembrane transport proteins
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α-aminoadipic acid
Entity
sodium/calcium exchanger protein
Entity
symporters
Entity
Na-K-Cl cotransporter
Entity
solute carrier family 4 member 1 (Diego blood group)
Protein
Solute carrier family 5 member 5
Protein
copper
Entity
sodium
Entity
protein
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potassium
Entity
proton
Entity
enzyme
Entity
Wikidata
Entity