SLC1A3
Sign in to saveAlso known as EA6, EAAT1, GLAST, GLAST1, solute carrier family 1 member 3
protein-coding gene in the species Homo sapiens
Gene data
SLC1A3- Name
- solute carrier family 1 member 3
- Type
- protein-coding
- Position
- 36,596,584–36,688,335 (+)
- Aliases
- EA6, EAAT1, GLAST, GLAST1
- Ensembl
- ENSG00000079215
- RefSeq RNA
- NM_001166695.3, NM_001166696.3, NM_001289939.2, NM_001289940.2, NM_001438454.1
- RefSeq protein
- NP_001160167.1, NP_001160168.1, NP_001276868.1, NP_001276869.1, NP_001425383.1
This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2014].
Gene Ontology
Biological process
Molecular function
L-glutamate transmembrane transporter activityL-glutamate transmembrane transporter activityL-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityhigh-affinity L-glutamate transmembrane transporter activityprotein binding
Pathways
Synaptic vesicle cycle - Homo sapiens (human)Glutamatergic synapse - Homo sapiens (human)Huntington disease - Homo sapiens (human)Neurotransmitter release cycleNeurotransmitter uptake and metabolism In glial cellsTransmission across Chemical SynapsesNeuronal SystemDiseaseAstrocytic Glutamate-Glutamine Uptake And MetabolismGlutamate Neurotransmitter Release Cycle
via MyGene.info
Gene · Ensembl
solute carrier family 1 member 3
- Symbol
- SLC1A3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:36,596,584-36,688,335
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 20882
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6507
- chromosome
- human chromosome 5
- genomic start
- 36596588
- genomic end
- 36688436
- cytogenetic location
- 5p13.2
- Commons category
- Excitatory amino acid transporter 1
- expressed in
- amygdala
Sources (8)
via Wikidata · CC0