SPECC1

Also known as CYTSB, HCMOGT-1, HCMOGT1, NSP, sperm antigen with calponin homology and coiled-coil domains 1, NSP5

Cytospin-B is a protein that, in humans, is encoded by the CYTSB gene.

In the Vinony graph

Within Vinony's link graph, SPECC1 is referenced by 5 other articles, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 17.

Its subject is documented across 5 Wikipedia language editions.

Gene data

SPECC1

Name: sperm antigen with calponin homology and coiled-coil domains 1
Type: protein-coding
Position: 20,008,865–20,319,026 (+)
Aliases: CYTSB, HCMOGT-1, HCMOGT1, NSP, NSP5
Ensembl: ENSG00000128487
RefSeq RNA: NM_001033553.3, NM_001033554.3, NM_001033555.3, NM_001243438.2, NM_001243439.2
RefSeq protein: NP_001028725.1, NP_001028726.1, NP_001028727.1, NP_001230367.1, NP_001230368.1

The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].