Also known as Oligo-1,6-glucosidase, SI, oligosaccharide alpha-1,6-glucosidase, sucrase-isomaltase, intestinal, Alpha-methylglucosidase, alpha-glucosidase
Sucrase-isomaltase is a bifunctional glucosidase (sugar-digesting enzyme) located on the brush border of the small intestine, encoded by the human gene SI. It is a dual-function enzyme with two GH31 domains, one serving as the isomaltase, the other as a sucrose alpha-glucosidase. It has preferential expression in the apical membranes of enterocytes. The enzyme's purpose is to digest dietary carbohydrates such as starch, sucrose and isomaltose. By further processing the broken-down products, energy in the form of ATP can be generated.
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).