TAS2R14
Sign in to saveAlso known as T2R14, TRB1, taste 2 receptor member 14
Taste receptor type 2 member 14 is a protein that in humans is encoded by the TAS2R14 gene.
In the Vinony graph
Vinony's link graph records 486 inbound references to TAS2R14, and connects out to PubMed, G protein-coupled recepteishon and Ensembl genome database project.
Vinony files it under Genes on human chromosome 12 and Human taste receptors.
Vinony links it to 6 Wikipedia language editions.
Gene data
TAS2R14- Name
- taste 2 receptor member 14
- Type
- protein-coding
- Position
- 10,937,408–11,171,573 (−)
- Aliases
- T2R14, TRB1
- Ensembl
- ENSG00000261984
- RefSeq RNA
- NM_023922.2
- RefSeq protein
- NP_076411.1
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
taste 2 receptor member 14
- Symbol
- TAS2R14
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:10,937,408-11,171,573
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 87013
- cytogenetic location
- 12p13.2
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/50840
- chromosome
- human chromosome 12
- genomic start
- 10937408
- genomic end
- 11324172
Sources (4)
via Wikidata · CC0
~5 min read
Encyclopedic overview
10 sectionsContents
- Gene
- SNPs
- Site-directed mutagenesis
- Signal transduction pathways
- Ligands
- Tissue distribution
- Function
- See also
- References
- Further reading
Taste receptor type 2 member 14 is a protein that in humans is encoded by the TAS2R14 gene.
Taste receptors for bitter substances (T2Rs/TAS2Rs) belong to the family of G-protein coupled receptors and are related to class A-like GPCRs. There are 25 known T2Rs in humans responsible for bitter taste perception.
Excerpted from Wikipedia’s “TAS2R14” article, available under the CC BY-SA 4.0 licence.