TAS2R31
Sign in to saveAlso known as T2R31, T2R44, T2R53, TAS2R44, taste 2 receptor member 31
Taste receptor, type 2, member 31, also known as TAS2R31, is a protein which in humans is encoded by the TAS2R31 gene. This bitter taste receptor has been shown to respond to saccharin in vitro.
In the Vinony graph
Vinony's link graph records 485 inbound references to TAS2R31, and connects out to PubMed, Ensembl genome database project and cell surface receptor.
It is catalogued under topics including Genes on human chromosome 12 and Human taste receptors.
Vinony links it to 6 Wikipedia language editions.
Gene data
TAS2R31- Name
- taste 2 receptor member 31
- Type
- protein-coding
- Position
- 11,030,387–11,031,407 (−)
- Aliases
- T2R31, T2R44, T2R53, TAS2R44
- Ensembl
- ENSG00000256436
- RefSeq RNA
- NM_176885.2
- RefSeq protein
- NP_795366.2
TAS2R44 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Mar 2009].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
taste 2 receptor member 31
- Symbol
- TAS2R31
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:11,030,387-11,031,407
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 136304
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/259290
- chromosome
- human chromosome 12
- genomic start
- 11182986
- genomic end
- 11184006
- cytogenetic location
- 12p13.2
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Taste receptor, type 2, member 31, also known as TAS2R31, is a protein which in humans is encoded by the TAS2R31 gene. This bitter taste receptor has been shown to respond to saccharin in vitro.
TAS2R31 is also expressed in the smooth muscle of human airways, along with several other bitter taste receptors. Their activation in these cells causes an increase in intracellular calcium ion, which in turn triggers the opening of potassium channels which hyperpolarize the membrane and cause the smooth muscle to relax. Hence, activation of these receptors leads to bronchodilation.
Excerpted from Wikipedia’s “TAS2R31” article, available under the CC BY-SA 4.0 licence.