TASP1

Name

taspase 1

Type

protein-coding

Aliases

C20orf13, SULEHS, dJ585I14.2

This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image

Protein TASP1 PDB 2a8i.png

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