MARK2

Also known as EMK-1, EMK1, PAR-1, Par-1b, Par1b, microtubule affinity regulating kinase 2

Serine/threonine-protein kinase MARK2 is an enzyme that in humans is encoded by the MARK2 gene.

In the Vinony graph

Vinony's link graph records 302 inbound references to MARK2, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It sits within the topics EC 2.7.11 and Genes on human chromosome 11.

Vinony links it to 5 Wikipedia language editions.

Gene data

MARK2

Name: microtubule affinity regulating kinase 2
Type: protein-coding
Position: 63,838,852–63,911,020 (+)
Aliases: EMK-1, EMK1, MRD76, PAR-1, Par-1b, Par1b
Ensembl: ENSG00000072518
RefSeq RNA: NM_001039469.3, NM_001163296.2, NM_001163297.2, NM_004954.5, NM_017490.4
RefSeq protein: NP_001034558.2, NP_001156768.1, NP_001156769.1, NP_004945.4, NP_059672.2

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009].