TGM2

Name

transglutaminase 2

Type

protein-coding

Position

38,127,385–38,168,463 (−)

Aliases

G(h), TG(C), TGC, hTG2, tTG

Ensembl

ENSG00000198959

RefSeq RNA

NM_001323316.2, NM_001323317.2, NM_001323318.2, NM_004613.4, NM_198951.3

RefSeq protein

NP_001310245.1, NP_001310246.1, NP_001310247.1, NP_004604.2, NP_945189.1

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

transglutaminase 2

Symbol

TGM2

Biotype

Protein coding

Organism

Homo sapiens

Location

20:38,127,385-38,168,463

Strand

Reverse (−)

Assembly

GRCh38