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thiram

Structure via PubChem · Public domain (PubChem)

EntityQ416572· pop 15· linked from 45 articles

thiram

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Also known as bis(dimethylthiocarbamoyl) disulfide, tetramethylthiuram disulfide, thiuram, [Me2NC(S)S]2, TMTD, N,N'-(dithiodicarbonothioyl)bis(N-methylmethanamine), tetramethylenethiuram disulfide

Thiram is the simplest thiuram disulfide and the oxidized dimer of dimethyldithiocarbamate. It is used as a fungicide, ectoparasiticide to prevent fungal diseases in seed and crops and similarly as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents and deer. It is effective against Stem gall of coriander, damping off, smut of millet, neck rot of onion, etc. Thiram has been used in the treatment of human scabies, as a sun screen and as a bactericide applied directly to the skin or incorporated into soap.

Chemical data

Formula
C6H12N2S4
Molecular weight
240.4 g/mol
IUPAC name
dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate
SMILES
CN(C)C(=S)SSC(=S)N(C)C
InChIKey
KUAZQDVKQLNFPE-UHFFFAOYSA-N
XLogP
1.7
Polar surface area
121 Ų
H-bond donors
0
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
parasitic infection

via ChEMBL · EBI

Research

1,358 papers

via PubMed

Wikidata facts

Subclass of
chemical compound
Has part
carbon
Mass
239.988
Show 12 more facts
chemical formula
C₆H₁₂N₂S₄
canonical SMILES
CN(C)C(=S)SSC(=S)N(C)C
time-weighted average exposure limit
5
NIOSH Pocket Guide ID
0612
density
1.29
immediately dangerous to life or health
100
melting point
150
vapor pressure
0.000008
solubility
0.003
World Health Organisation international non-proprietary name
thiram
subject has role
mutagen
Commons category
Thiram
Sources (4)

via Wikidata · CC0

~2 min read

Encyclopedic overview

5 sections
Contents
  • Usage
  • Chemical properties
  • Toxicity
  • References
  • External links

Thiram is the simplest thiuram disulfide and the oxidized dimer of dimethyldithiocarbamate. It is used as a fungicide, ectoparasiticide to prevent fungal diseases in seed and crops and similarly as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents and deer. It is effective against Stem gall of coriander, damping off, smut of millet, neck rot of onion, etc. Thiram has been used in the treatment of human scabies, as a sun screen and as a bactericide applied directly to the skin or incorporated into soap.

Thiram is also used as a sulfur source and secondary accelerator the sulfur vulcanization of rubbers.

Excerpted from Wikipedia’s “thiram” article, available under the CC BY-SA 4.0 licence.

Gallery (2)

Available in 14 languages

via Wikidata sitelinks · CC0